pentobarbital will lower the extent or outcome of terbinafine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lower the extent or outcome of amlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
fentanyl transmucosal and pentobarbital each increase sedation. Stay clear of or Use Alternate Drug. Restrict use to patients for whom option therapy selections are inadequate
pentobarbital will reduce the extent or effect of amiodarone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the extent or influence of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the extent or influence of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Strong or moderate CYP3A4 inducers may maximize charge of diazepam elimination; consequently, efficacy of diazepam may very well be reduced.
As medical facts regarding the usage of pentobarbital throughout breastfeeding are lacking, it's advisable to look at choice agents, specially when nursing a new child or preterm toddler.[seventeen]
pentobarbital will reduce the extent or outcome of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to a reduce in fentanyl plasma concentrations, insufficient efficacy or, quite possibly, advancement of the withdrawal syndrome inside of a patient who has produced Bodily dependence to fentanyl.
pentobarbital will lower the extent or result of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lessen the level or effect of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Unidentified.
pentobarbital will decrease the extent or result of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib can be a sensitive CYP3A4 substrate. Coadministration with powerful or reasonable CYP3A4 inducers is contraindicated.
pentobarbital will reduce the level or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the level or influence of piroxicam by affecting hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Not known.
Contraindicated (one)pentobarbital will minimize the extent or click here effect of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers may result in lowered serum concentrations and lack of antimalarial efficacy